Preheat oven to 400°F (200°C) and line a baking sheet with parchment paper or a wire cooling rack.
Place the flour in a shallow bowl. In a second bowl, beat the eggs. In a third bowl, combine panko, parmesan cheese, garlic powder, oregano, salt, and pepper.
Pat the chicken tenders dry with paper towels to ensure maximum coating adhesion.
Dredge each tenderloin in the flour, shaking off any excess.
Dip the floured tenderloin into the egg wash, allowing the excess to drip off.
Press the tenderloin firmly into the panko-parmesan mixture until fully coated on all sides.
Arrange the breaded chicken on the prepared baking sheet and lightly coat the tops with cooking spray.
Bake for 10 minutes, then flip the tenders and bake for an additional 8 to 10 minutes until the internal temperature reaches 165°F (74°C) and the crust is golden brown.
Remove from the oven and allow to rest for 3 minutes before serving.