In a small bowl, whisk together the mayonnaise, yellow mustard, Dijon mustard, honey, and lemon juice until fully emulsified; refrigerate until service.
Set up a three-stage dredging station using shallow containers: one with flour mixed with salt, pepper, garlic powder, and paprika; one with eggs beaten with milk; and one with Panko breadcrumbs.
Dredge each chicken tender in the seasoned flour, shaking off excess, then submerge in the egg wash, and finally press into the Panko breadcrumbs until completely and evenly coated.
Heat vegetable oil in a heavy-bottomed skillet over medium-high heat until it reaches an optimal frying temperature of 350 degrees Fahrenheit.
Fry chicken tenders in batches to avoid crowding the pan, cooking for approximately 3 to 4 minutes per side until the crust is golden brown and the internal temperature reaches 165 degrees Fahrenheit.
Transfer the fried tenders to a wire rack set over a baking sheet to drain excess oil while maintaining crispness.
Serve the warm chicken tenders immediately with the chilled honey mustard dipping sauce.