Preheat oven to 400°F (200°C) and line a baking sheet with parchment paper.
In a large mixing bowl, combine ground beef, ground pork, breadcrumbs, egg, milk, onion powder, garlic powder, salt, and pepper.
Form the mixture into 1-inch balls (approximately 40 meatballs) and place them on the prepared baking sheet.
Bake meatballs for 15-18 minutes or until cooked through and slightly browned.
While meatballs bake, combine cranberry sauce, chili sauce, brown sugar, orange juice, and soy sauce in a large saucepan over medium heat.
Whisk the sauce until smooth and bring to a gentle simmer for 5 minutes.
Transfer the baked meatballs into the saucepan with the sauce.
Toss meatballs to coat thoroughly and simmer on low for an additional 10 minutes before serving.